This study aimed to identify the Organizational Factors and Their Impact on Enhancing Entrepreneurial Orientation at Palestinian Universities in the Gaza Strip". It also sought to identify the most prominent organizational factors influencing the achievement of entrepreneurial orientations in Palestinian universities, and to analyze the statistically significant differences among the mean estimates of the study sample regarding the degree of effectiveness of organizational factors, based on variables such as gender, employment status, academic degree, and years of service. The study adopted the descriptive-analytical approach. The study population consisted of administrative and academic staff at Palestinian universities in the Gaza Strip, totaling (4,460) individuals. A questionnaire was distributed to (354) administrative and academic staff members, of which (271) completed questionnaires were retrieved. The results revealed that organizational factors in Palestinian universities are highly available, with a total effectiveness score of 93.04%, reflecting an advanced level of coordination and planning within these institutions. Regarding the organizational structure, it recorded a mean of (0.788), indicating the role of organizational structure in enhancing coordination among departments and employees; it ranked first among the studied domains and was classified as "Very Good." As for the leadership style, it recorded a mean of (0.766), indicating that the adopted leadership styles support effective participation and encourage cooperation among individuals. Among the most important recommendations are: strengthening the organizational structure by clearly distributing roles, using modern technologies to ensure coordination and efficiency, enhancing cooperation with international universities, developing e-learning, and stimulating student entrepreneurship................................ Keywords: ...................Organizational Factors, Entrepreneurial Orientations, Entrepreneurship Strategies, Entrepreneurship.