المجلة الدولية للعلوم والتقنية

Objective: Hypertension and diabetes are closely related morbidities. There is a researches examining the relationship between blood pressure (BP) and HbA1c level newly and among older diabetes mellitus. The objective of the current study was to investigate the association of high BP and HbA1c level. Materials and methods: A cross-sectional study, 48 diabetic patients in (Diabetes & Endocrinology Center Tripoli – Libya) were chosen. Blood pressure was measured using a mercury sphygmomanometer, Serum HbA1c and Lipids were measured by enzymatic method COBAS INTEGRA. HbA1c was measured by immunoturbidimetrically COBAS INTEGRA. Correlation (Pearson) analysis was used to explore the association between hypertension and hyperglycemia. Independent risk factors for systolic and diastolic BP were analyzed using correlation. Results: Subjects in HbA1c group newly type-II diabetes mellitus (n = 24) and old type-II diabetes mellitus (n = 24), as compared with normal HbA1c (n = 24). There was significant correlation between glycated haemoglobin (HbA1c) and Systolic blood pressure (SBP) (r=0.308*, P=0.033), Diastolic blood pressure (DBP) (r=0.137, P=0.353), but there were strong significant correlations between glycated haemoglobin (HbA1c) and Systolic blood pressure (SBP) (r=0.607**, P=0.001), Diastolic blood pressure (DBP) (r=0.203, P=0.166), had a significant higher risk for hypertension, respectively. correlation analysis revealed HbA1c was an independent factor of systolic and diastolic BP. Conclusions: in study present a relationship between hyperglycemia and hypertension in a type-II diabetes, our findings suggest that hyperglycemia as well as higher HbA1c within the old type-II diabetes range is associated with a higher prevalence of hypertension independent of other cardiovascular risk.