المجلة الدولية للعلوم والتقنية

Background: Tobacco cigarette smoking is one of the major leading causes of death throughout the world. Smoking has both acute and chronic effect on haematological parameters. The aim of the present study was to assess the extent of adverse effects of cigarette smoking on biochemical characteristics in healthy smokers. Objective: To compare the effect of cigarette smoking on red blood cell count, white blood cell count, hemoglobin and hematocrit levels between smokers and non smokers. Subjects and Method: fifty subjects participated in this study, 40 smokers and 10 non-smokers. The smokers were regularly consuming 10-20 cigarettes per day for at least 3 years. Complete blood cell count was analyzed by Mindary Bc-2800 fully automatic haematological analyzer. Results:The smokers had significant higher levels of hemoglobin (p=0.001), white blood cell (p=0,003), hematocrit (p=0,007), and red blood cell (p=0.006) in comparison to non-smokers.While we did not find any significant changes in platelets (PLT) between smokers and non-smokers (P=0.061). Conclusion: In conclusion, in this study showed that continuous cigarette smoking has severe adverse effects on haematological parameters (e.g., hemoglobin, white blood cells count, mean corpuscular hemoglobin concentration, red blood cells count, hematocrit) and these alterations might be associated with a greater risk for developing atherosclerosis, polycythemia vera, chronic obstructive pulmonary disease and/or cardiovascular diseases. Recommendations: We recommend the study of impact of quitting the smoking or tobacco products on hematological parameters analyzed in the present study.