المجلة الدولية للعلوم والتقنية

Infective endocarditis occurs worldwide; Endocarditis is usually caused by an infection. Bacteria, fungi or other microorganisms get into the bloodstream and attach to damaged areas in the heart. Infective endocarditis is a relatively uncommon disease with a high mortality rate. Things that make you most likely to get endocarditis are artificial cardiac valves, damaged cardiac valves or congenital cardiac disease, we analyzed 57 cases including 11 cases were males and 6 cases of females from MAY 2021 to OCT 2023.variables were collected from the patients included age, gender and blood culture which recorded (19.2%), among of the positive samples were males with (10.5%), Negative samples were recorded in 40 patients, at a rate of 70.1%, as the number of female cases was 23 and males were 17. The rate of isolates was higher among the age group (46-56), (57-67), was 5 patients with similar percentages (8.7%). while an age group (35-45) don't record any case of isolates. the isolated Gram-positive bacteria were (82.3%) Staphylococci species which amounted to (76.5%) as the most common cause of infective endocarditis, Staphylococcus aureus was more bacteria isolated than patient samples with percentage (23.5%), followed by Gram-negative bacteria Klebsiella pneumonia, which amounted to (17. 6%).The bacteria have recorded high sensitivity to Azithromycin, Impienem, Meropenem, Augmantin ,teicoplanin and vancomycin which was the drug of choice. while the highest bacterial resistance was recorded to Cephalothin,Cefoxitin, Ticarcillin Erthromycin and penicillin. Keywords: Endocarditis, Bacterial infection, Heart disease, Heart valves.