International Science and Technology Journal
Published by
Under supervision of
Open Access Journal
ISSN: 2519-9854 (Online)
ISSN: 2519-9846 (Print)
A peer-reviewed and open access journal concerned with publishing researches and studies in the field of applied sciences and engineering
Correlation between Glycated Hemoglobin Levels with, Serum Glucose and Serum Lipid Levels in Type-II Diabetes Mellitus in Libyan
| Researcher(s): | - Dr. Omar. A. Aghil
- Dr. Abdulkarim. A. Zwawi
- Dr. Bahlol. B. Masoud
- Fathi. A. Alsharif
- Akram. M. Elhegagi
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| Institution: | Faculty of medical technology university of Tripoli |
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| Field: | العلوم الطبية و الصحية |
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| Published in: | 12th volume - December 2017 |
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الملخص
لهدف: داء السكري هو المرض الأيضي الأكثر شيوعا. واحدة من أكثر المشاكل شيوعا في مرضى السكري هو مرض القلب والأوعية الدموية تصلب الشرايين التي يسببها الدهون. ضعف التمثيل الغذائي للدهون الناتجة عن فرط سكر الدم غير المنضبط متورط في مضاعفات القلب والأوعية الدموية لدى مرضى السكري الجدد. كما اعتبر الهيموجلوبين الغليكاتي (HbA1c) عامل خطر مستقل لأمراض القلب والأوعية الدموية. هدفت هذه الدراسة إلى دراسة العلاقة بين HbA1c وسكر الدم الصوم (فبس) مع مستويات الدهون في الدم في داء السكري من النوع الثاني.
Abstract
Abstract
Objective: Diabetes mellitus is the most common metabolic disease. One of the most common problems in diabetic patients is atherosclerotic cardiovascular disease which is induced by hyperlipidemia. Impaired lipid metabolism resulting from uncontrolled hyperglycemia has been implicated in cardiovascular complications in diabetic new patients. Also, glycated hemoglobin (HbA1c) has been regarded as an independent risk factor for cardiovascular disease. The aim of this study was to examine the correlation between HbA1c, fasting blood sugar (FBS) with serum lipid levels in type 2 diabetes.
Materials and Methods: In this study, 80 diabetic patients in (Diabetes & Endocrinology Center Tripoli – Libya) were chosen. FBS, HbA1c and serum lipid levels were analyzed in patients. Serum Lipids and glucose were measured by enzymatic method COBAS INTEGRA. HbA1c was measured by immunoturbidimetrically COBAS INTEGRA.
Results: There was significant correlation between FBS and Total Cholesterol (TC) (r=0.28, P=0.001), but there were no correlations between Glycated haemoglobin (HbA1c) and TC (r=0.13, P=0.28), HbA1c and Cholesterol (CH) (P=0.71, r=-0.11), HbA1c and HDL (P=0.26 r=-0.11) and HbA1c with LDL (P=0.84, r=-0.05).