International Science and Technology Journal

Scientific studies indicate the use of medicinal plants as antibiotics for some pathogenic fungi, as they do not cause side effects when used in the specified doses, either by extracting the active ingredients from each plant alone or by extracting them from more than one plant species. Thus, this study targeted the effect of inhibiting the active ingredients of Mesembryanthemum crystallinum L. on the activity of the fungus Candida albicans using polar solvents, namely water, ethyl alcohol and methanol, and detecting its content of active compounds. The results showed that the Ghassoul plant contains saponins and resins, as well as alkaloids, glycosides, flavonoids and tannins in the aqueous extract, while its content was phenols, proteins, amino acids and tannins in the ethylene and methanol alcoholic extracts. The results also showed that the ethyl alcohol extract has an effect on the activity of Candida albicans, as the highest average inhibition diameter was 17 mm, and thus it can be used as a new antifungal material, while the methanol and aqueous extracts of Ghassoul have the lowest average inhibition diameters on Candida albicans, which are 16 mm and 15 mm, respectively........... Keywords: .......medicinal plants, Ghassoul plant, aqueous extract, alcoholic extract, Candida albicans.